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In the twenty-first century, science will continue to have a profound influence on people’s daily lives and well-being. People’s attitudes toward science and the ways in which they engage with scientific content will impact everything from their curiosity about scientific discoveries to evidence-informed decision-making to their desire to participate in science. The three publications from the Public Face of Science Initiative have highlighted a breadth of critical resources, including public opinion polling, academic literature, databases, institutions, professional organizations, programs, and experts that show we are not starting from a deficit in this space. We are at a moment in time when the enthusiasm and support for science communication and engagement can be harnessed for greater impact through wide­scale efforts to build capacity. The goals and priority areas in this report offer a starting point for long-term action.