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Investigator, Howard Hughes Medical Institute; Francis Crick Professor and Laboratory Head, Computational Neurobiology Laboratory. His research seeks to understand the computational resources of brains and to build linking principles from brain mechanisms to behavior using computational models. His laboratory uses both experimental and modeling techniques to study the biophysical properties of synapses and neurons and the population dynamics of large networks of neurons. Some of the central issues he examines include how dendrites integrate synaptic signals in neurons, how networks of neurons generate dynamical patterns of activity, how sensory information is represented in the cerebral cortex, how memory representations are formed and consolidated during sleep, and how visuo-motor transformations are adaptively organized.Member of the Institute of Medicine of the National Academies, the National Çï¿ûÊÓƵ of Sciences, and the National Çï¿ûÊÓƵ of Engineers.