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Fred Hutchinson Cancer Research Center, Seattle, Washington; University of Washington, Seattle, Washington~ Past President and Director; Professor of Medicine and Laboratory Medicine. Recognized for contributions to the field of infectious diseases and global health. Research established the pathophysiologic framework for understanding the worldwide pandemic of genital herpes (HSV-2). Pioneered the development of antiviral therapy for chronic viral infections and demonstrated the role and underlying mechanism by which HSV-2 increases HIV acquisition and transmission. With Gertrude Elion, first to demonstrate that an antiviral compound specific for a viral specified enzyme could be safely and effectively administered to control a chronic viral infection (HSV-2). Studies provided the foundation for the subsequent development of effective antiviral therapy for Hepatitis B and HIV. Founding head of the AIDS Clinical Trials Group under whose leadership AZT and combination antiretroviral therapy were shown to reduce maternal fetal transmission of HIV and to reduce HIV mortality, respectively. Serves as a leader of the HIV Vaccine Trials Network (HVTN). Tireless in seeking the development of HIV vaccines and oversaw the development of scientific collaborations in fourteen countries on five continents in that pursuit.~