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Cagla Eroglu, the Chancellor's Distinguished Professor of Cell Biology and Neurobiology at Duke University, investigates the cellular and molecular underpinnings of how synaptic connections between neurons are established and remodeled in the mammalian brain by the bidirectional signaling between neurons and cells called astrocytes.

Eroglu, a Howard Hughes Medical Institute investigator and vice chair of research in the Department of Cell Biology, has shown that astrocytes, previously thought to be inert support cells, help construct an intricate web of neural circuitry, and that astrocyte dysfunction has been connected to devastating diseases like autism, schizophrenia and epilepsy.