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Blanton Tolbert

Penn Institute for RNA Innovation

Blanton Tolbert leads HHMI’s Center for the Advancement of Science Leadership and Culture where he directs a portfolio of current and new programs at the undergraduate and graduate level, an initiative to better equip HHMI scientists to provide culturally aware mentorship, a curriculum to grow scientists’ skills to maintain inclusive environments, and activities to develop strategic equity-centered initiatives and partnerships. Tolbert is also a Professor of Biochemistry and Biophysics at University of Pennsylvania. The research in the Tolbert group focuses on the biochemical mechanisms by which RNA viruses replicate within the cellular environment. His group leverages their fundamental understanding of the molecular biology of these viruses to identify novel targets for therapeutic intervention. The team has collaborated with colleagues to develop compounds with the potential to delay or halt the replication of SARS-CoV-2 and EV-A71.

Tolbert earned a BS in chemistry at University of South Carolina and a PhD in biophysics and structural biology at University of Rochester. He was an HHMI postdoctoral fellow at University of Maryland, Baltimore County, with HHMI Investigator Michael Summers. In 2016, Tolbert received the inaugural Morton L. Mandel Award for Excellence in Research and Service from the CWRU chemistry department. In 2023, he was recognized by the International Society for Antiviral Research with the Diversity in Science and Excellence Award. 

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