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Astronaut Jessica Meir made history in October 2019 when she participated in the first all-female spacewalk. After 205 days in the isolation of space, she returned to a planet experiencing its own form of isolation – the global COVID-19 pandemic. As an astronaut and a marine biologist, Meir’s research into the impact of extreme environments has brought her to the depths of the Antarctic and the heights of space. Meir joined Brian Keating, Chancellor’s Professor of Physics at the University of California, San Diego, her alma mater, for a conversation about these adventures and the perspectives they provide about our world.